SynBio Canada
SynBio Canada

Academic Profiles

Academic Profiles

Posts tagged #industry
Dr. Bogumil Karas

Assistant Professor, Biochemistry, University of Western Ontario / CEO Designer Microbes

Email Address: bkaras@uwo.ca

Bio: Research in the Karas lab is focused on developing innovative genetic tools to enable the engineering of microbes to produce medicines, DNA storage technologies, food and next-generation fuels. We are using a multi-host system to perform in vivo gene deletions, additions and replacements. This approach was designed to take advantage of existing genetic tools developed for model organisms, including Escherichia coli and Saccharomyces cerevisiae. Currently, we are developing novel tools for eukaryotic algae: Phaeodactylum tricornutum, Thalassiosira pseudonana and soil bacterium Sinorhizobium meliloti.

Website: https://www.schulich.uwo.ca/biochem/people/bios/Karas.html

Twitter: @BogumilKaras

Dr. Radhakrishnan Mahadevan
Mahadevan-small.jpg

Professor, Associate Chair & Graduate Studies Coordinator, University of Toronto

Email Address: krishna.mahadevan@utoronto.ca

Bio: Our group primarily works on engineering metabolism in bacteria and yeast to produce chemicals and therapeutic molecules. Through the use of computational strategies on genome scale metabolic models of these organisms, we identify genetic intervention strategies to enhance target molecule production. Synthetic biological tools help us assemble and engineer pathways in microorganisms. We use synthetic gene regulatory circuits to dynamically control metabolism in host organisms. The ability to dynamically control metabolism based on environmental inputs finds application in a variety of different areas including therapeutics and industrial biotechnology.

Website: www.lmse.utoronto.ca

Twitter: @LMSE_UofT