SynBio Canada
SynBio Canada

Academic Profiles

Academic Profiles

Posts tagged #geneediting
Dr. Steven Hallam
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Professor, University of British Columbia

Email Address: shallam@mail.ubc.ca

Bio: Dr. Steven Hallam is a University of California Santa Cruz and MIT trained molecular biologist, microbial ecologist, entrepreneur, and innovator with over 20 years experience in field and laboratory research at disciplinary interfaces. He is a Professor in the Department of Microbiology and Immunology, former Canada Research Chair in Environmental Genomics and a Leopold Leadership Fellow. He is also a program faculty member in the Bioinformatics and Genome Sciences and Technology training programs at UBC.

Dr. Hallam directs the ECOSCOPE innovation ecosystem consisting of an NSERC CREATE training program, a research network, a core facility for high-throughput screening and a curriculum development initiative in data science based on four research and training pillars: i) microbial ecology, ii) biological engineering, iii) data science, and iv) networking and entrepreneurship. His research intersects these program pillars with specific emphasis on the creation of functional screens and computational tools that reveal hidden metabolic powers of uncultivated microbial communities with direct application to biocatalyst discovery and pathway engineering.

Website: http://ecoscope.ubc.ca

Twitter: @HallamLab

Dr. Bogumil Karas

Assistant Professor, Biochemistry, University of Western Ontario / CEO Designer Microbes

Email Address: bkaras@uwo.ca

Bio: Research in the Karas lab is focused on developing innovative genetic tools to enable the engineering of microbes to produce medicines, DNA storage technologies, food and next-generation fuels. We are using a multi-host system to perform in vivo gene deletions, additions and replacements. This approach was designed to take advantage of existing genetic tools developed for model organisms, including Escherichia coli and Saccharomyces cerevisiae. Currently, we are developing novel tools for eukaryotic algae: Phaeodactylum tricornutum, Thalassiosira pseudonana and soil bacterium Sinorhizobium meliloti.

Website: https://www.schulich.uwo.ca/biochem/people/bios/Karas.html

Twitter: @BogumilKaras

Dr. Vincent Martin
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Professor, Concordia University and Co-Director, Centre for Applied Synthetic Biology

Email Address: vincent.martin@concordia.ca

Bio: We are synthetic biologists with a strong penchant for metabolic engineering and industrial strain improvement. We like yeast but will play with other unicellular bugs as well.

Website: https://www.concordia.ca/research/casb.html

Dr. Scott McComb
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Research Officer, National Research Council of Canada; University of Ottawa

Email Address: scott.mccomb@nrc-cnrc.gc.ca

Bio: Chimeric antigen receptor T cells (CAR-T) are an exciting new avenue to redirect immune cells to target and kill cancer. While breakthroughs in CAR-T therapy have led to life-saving treatments for patients with previously incurable leukemia, such therapies have been less successful against solid tumours. Moreover, the determinants of long term cancer regression in CAR-T treated patients are not yet well understood. Using genome editing, we are dissecting the mechanisms of programmed cell death and other immune signalling pathways in T cells in order to improve their effectiveness against cancer. Our long term goal is to create super-functional gene-edited cell therapies to treat currently intractable illnesses such as cancer and autoimmunity.

Website: https://med.uottawa.ca/bmi/people/mccomb-scott

Dr. Moira McQueen

Executive Director, Canadian Catholic Bioethics Institute, University of St Michael's College, University of Toronto, (LLB, M Div, PhD)

Bio: As a bioethicist, I am interested in the science and development of synthetic biology and in ethical questions that arise from its use, as well as in its impact on health care, the workforce and the environment.

Website: www.ccbi-utoronto.ca

Twitter: @moiramcqueen

Dr. Peter Zandstra
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Professor & Director, Michael Smith Laboratories, University of British Columbia / Professor, University of Toronto

Email Address: peter.zandstra@ubc.ca

Bio: Research in the Zandstra Laboratory is focused on the generation of functional tissue from somatic and pluripotent stem cells. Our quantitative, technology-driven approach strives to gain new insights into fundamental mechanisms that control stem cell fate and to develop robust technologies for the propagation of stem cells and their derivatives. We apply synthetic biology to understand and control cell fate decisions by manipulating the stem cells themselves (genome editing, gene circuit engineering) and their prospective niche (synthetic biomaterials, macro- and micro reactor technologies).

Website: http://stemcell.ibme.utoronto.ca/

Twitter: @PZandstra

Dr. Wei Zhang
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Assistant Professor, University of Guelph

Email Address: weizhang8182@gmail.com

Bio: My lab will open in July 2018 at the Department of Molecular and Cellular Biology, University of Guelph. We are creating synthetic proteins using bimolecular engineering approaches to accelerate understanding of biology and development of novel therapeutics.

Website: www.thezhanglab.com

Twitter: @WeiZhangTO